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Hypothyroidism causes the usual symptoms of fatigue and weight gain, and in patients with Graves disease, it has been anecdotally associated with worsening of thyroid ophthalmopathy.

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If a physician treats enough patients who are hyperthyroid, eventually he or she will encounter a patient who develops agranulocytosis or hepatitis from the antithyroid medications.

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During pregnancy, more-frequent TSH determinations are needed because of increasing needs secondary to an increase in binding protein levels and because of the importance of adequate treatment for normal neuropsychological development of the baby.

This is important to know since the most common cause of hyperthyroidism is Graves' disease and you need to make sure your antibody levels are very low before stopping meds.

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Specifically, according to research, methimazole and carbimazole can be taken up to 3 to 5 days before RAI without reducing the effectiveness of the RAI, but because PTU takes longer to clear out of your system, it should be stopped at least two weeks before RAI.

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TSH levels are high, and the TSH produced in both disorders is biologically more active than normal TSH.

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We conclude that carbimazole in a single daily dose is an effective method for treating hyperthyroidism in an area of mild iodine deficiency and its efficacy is comparable to divided dose therapy.

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